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!important;'><div class='rendered-post' style='max-width: 672px; margin: 0 auto;'><div class='bg-wt-background text-wt-text-on-background'><div style='padding-top:1.5rem; padding-bottom:1.5rem;'><style> .bh__byline_wrapper { font-size: .875rem; line-height: 1.25rem; vertical-align: middle; justify-content: space-between; display: block; } .bh__byline_social_wrapper { display: flex; margin-top: 0.5rem; align-items: center; } .bh__byline_social_wrapper > * + * { margin-left: 0.5rem; } @media (min-width: 768px) { .bh__byline_wrapper { display: flex; } .bh__byline_social_wrapper { margin-top: 0rem; } } </style><div id='web-header' style='padding-left: 2px; padding-right: 2px; color: var(--wt-text-on-background-color) !important; padding-bottom: 2rem;'><h1 style='font-size: 36px; font-family:'Trebuchet MS','Lucida Grande',Tahoma,sans-serif; line-height: 2.5rem; padding-bottom: 8px; font-weight: 700;'>Issue #6 - 🧬 Time machine </h1><h2 style='font-size: 20px; font-family:'Helvetica',Arial,sans-serif; line-height: 1.75rem; padding-bottom: 0px; font-weight: 400;'>Scientists reverse aging in human cells for first time</h2><div class='bh__byline_wrapper'><div><div style='display:flex;'><div style='display:flex; flex-direction:row; justify-content:flex-start;'><div style='display:flex;'></div><div style='display:flex; align-items:center;'><p style='left:24px;position:relative;font-family:'Helvetica',Arial,sans-serif;font-weight:400;font-size:14px;color: var(--wt-text-on-background-color);margin:0px;line-height:20px;'><span class='text-wt-text-on-background' style='opacity:0.75;'> January 15, 2026 </span></p></div></div></div></div><div class='bh__byline_social_wrapper'><a href='https://www.facebook.com/sharer/sharer.php?u=https%3A%2F%2Frenewal-weekly.beehiiv.com%2Fp%2Ftime-machine' target='_blank'><div style='max-width:28px;'><svg fill='none' height='100%' viewBox='0 0 212 212' width='100%' xmlns='http://www.w3.org/2000/svg'><circle cx='106.214' 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102.469ZM106.555 119.985C102.042 120.239 97.3533 118.213 97.1221 113.874C96.9507 110.657 99.4116 107.067 106.832 106.64C107.682 106.591 108.516 106.567 109.335 106.567C112.03 106.567 114.552 106.829 116.844 107.33C115.989 118.008 110.974 119.742 106.555 119.985Z' fill='#BAC2CE'></path></svg></div></a><a href='https://www.linkedin.com/sharing/share-offsite?url=https%3A%2F%2Frenewal-weekly.beehiiv.com%2Fp%2Ftime-machine' target='_blank'><div style='max-width:28px;'><svg fill='none' height='100%' viewBox='0 0 211 211' width='100%' xmlns='http://www.w3.org/2000/svg'><circle cx='105.5' cy='105.5' fill-opacity='0.15' fill='#9CA3AF' r='105.5'></circle><path d='M82.1892 75.4698C82.1892 80.1362 78.526 83.8026 73.8638 83.8026C69.2015 83.8026 65.5383 80.1362 65.5383 75.4698C65.5383 70.8034 69.2015 67.137 73.8638 67.137C78.526 67.137 82.1892 70.8034 82.1892 75.4698ZM82.1892 90.4689H65.5383V143.799H82.1892V90.4689ZM108.831 90.4689H92.1797V143.799H108.831V115.801C108.831 100.135 128.812 98.8017 128.812 115.801V143.799H145.463V110.134C145.463 83.8026 115.824 84.8026 108.831 97.8018V90.4689Z' fill='#BAC2CE'></path></svg></div></a></div></div></div><div id='content-blocks'><div style="padding: 8px 2px 8px 2px;"><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><table style="width: 100%; padding-bottom: 12px; margin-bottom: 16px; font-size: 13px; color: #6B7280; border-bottom: 1px solid #E5E7EB; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;" cellpadding="0" cellspacing="0"><tbody><tr><td style="text-align: left; width: 50%;">Issue #6</td><td style="text-align: right; width: 50%;">Jan 15, 2026</td></tr></tbody></table><div style="margin-bottom: 16px; border-radius: 8px; overflow: hidden;"><a href="https://www.renewalweekly.com?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer"><img src="https://i.imgur.com/dUcJfmW.jpg" alt="Renewal Weekly" style="width: 100%; display: block;"></a></div><table style="width: 100%; padding: 16px 0; margin-bottom: 16px;" cellpadding="0" cellspacing="0"><tbody><tr><td style="text-align: center; vertical-align: middle;"><span style="font-size: 11px; font-weight: 600; letter-spacing: 1px; color: #6B7280; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; margin-right: 12px;">PRESENTED BY</span><a href="https://viomehq.sjv.io/c/3937227/1384802/13051?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener sponsored" style="vertical-align: middle;"><img src="https://i.imgur.com/ulqtEkV.png" alt="Partner" style="max-width: 120px; max-height: 32px; display: inline-block; vertical-align: middle;"></a></td></tr></tbody></table><div class="rw-body" style="font-size: 16px; line-height: 1.6; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><strong>Good morning</strong> — and a warm welcome if you're joining us from one our stem cell partners. This is <a href="https://www.renewalweekly.com?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">Renewal Weekly</a>, your new Thursday home for stem cell research, regenerative therapies, and the longevity science that's actually worth your time. We share <a href="https://renewalweekly.com/issues/issue-1-cell-service-restored?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">interesting facts</a>, new treatments and clinical trials. Five minutes a week. Glad to have you. </div><div style="margin-top: 16px;"><p style="font-size: 16px; font-weight: 600; margin-bottom: 12px; font-family: 'Trebuchet MS', Helvetica, sans-serif;">In today's edition:</p><ul style="list-style: none; padding: 0; margin: 0;"><li style="margin-bottom: 6px; font-size: 16px; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"> 👁️ The sauna redemption arc </li><li style="margin-bottom: 6px; font-size: 16px; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"> 🧬 Age reversal breakthrough </li><li style="margin-bottom: 6px; font-size: 16px; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"> 💊 Cellular reset mechanism </li><li style="margin-bottom: 6px; font-size: 16px; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"> ❤️ Heart therapy projections </li></ul></div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">THIS WEEK'S BIG STORY</p><h2 style="font-size: 22px; font-weight: 700; margin: 0 0 6px 0; line-height: 1.3; font-family: 'Trebuchet MS', Helvetica, sans-serif;">The most measured man alive just released his year-end review</h2><div style="margin: 12px -24px;"><a href="https://www.youtube.com/watch?v=1m6FDwmjEF0&utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer"><img src="https://imgur.com/rzCHGGW.jpg" alt="Bryan Johnson health protocol" style="width: 100%; display: block;"></a></div><p style="font-size: 11px; color: #6B7280; font-style: italic; margin: 4px 0 12px 0;">Jan 15, 2026 | Blueprint</p><div style="font-size: 16px; line-height: 1.6;"><p style="margin: 0 0 8px 0;">Bryan Johnson—the tech millionaire who goes to bed at 8:30pm, swallows 100+ pills daily, and once publicly compared his nighttime erection data to his teenage son's—just <a href="https://www.youtube.com/watch?v=1m6FDwmjEF0&utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">released</a> his annual health recap. And yes, it's exactly as intense as you'd expect from someone who spends <strong>$2 million a year</strong> trying to live forever.</p><p style="margin: 0 0 8px 0;">The headlines: blood pressure lower than 90% of 18-year-olds, telomeres regenerating like a 12-year-old's, and an epigenetic aging speed of just <strong>0.48</strong>. His vascular function? "Late teens/early 20s." The man is 47.</p><p style="margin: 0 0 8px 0;"><strong style="font-size: 18px; display: block; margin: 16px 0 8px 0;">Magic mushrooms enter the chat</strong></p><p style="margin: 0 0 8px 0;">Johnson's wildest claim: psilocybin might be a <a href="https://ascpt.onlinelibrary.wiley.com/doi/10.1002/cpt.557?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">metabolic reset button</a> for the brain. After two doses of magic mushrooms over three months, his blood sugar control jumped from the top 2% to the top 0.25%—better than <strong>99.75%</strong> of people aged 18-25. His team is calling it a "first-in-world observation in humans." Take that with whatever grain of salt feels appropriate for a sample size of one.</p><p style="margin: 0 0 8px 0;"><strong style="font-size: 18px; display: block; margin: 16px 0 8px 0;">The sauna redemption arc</strong></p><p style="margin: 0 0 8px 0;">Dry sauna turned out to be Johnson's breakout star. Just 15 sessions at 200°F apparently <a href="https://www.mayoclinicproceedings.org/article/S0025-6196(18)30275-1/fulltext?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">slashed environmental toxins</a>, knocked a decade off his vascular age, and—here's where it gets very Bryan Johnson—reduced microplastics in his blood and ejaculate by <strong>85%</strong>. (Yes, he measured that. Of course he did.)</p><p style="margin: 0 0 8px 0;">Meanwhile, the graveyard of failed experiments grew longer. SLU-PP-332 wrecked his sleep. Plasmalogens did basically nothing. Methylene blue made him worse at another therapy he liked better. Even with unlimited resources, most interventions don't work.</p><p style="margin: 0 0 8px 0;"><strong style="font-size: 18px; display: block; margin: 16px 0 8px 0;">What's actually useful here</strong></p><p style="margin: 0 0 8px 0;">Buried beneath the erection trackers and mushroom trips is a surprisingly boring takeaway: sleep, nutrition, and exercise still do most of the heavy lifting. Johnson admits as much. The frontier therapies are add-ons, not replacements. And unless you've got a medical team and millions to burn, that's probably where your focus should stay.</p><p style="margin: 0 0 8px 0;">Still, if psilocybin's metabolic effects hold up in actual clinical trials, 2025 might be remembered as the year someone accidentally discovered something important while trying very hard not to die.</p></div><div style="margin-top: 16px; padding-top: 12px; border-top: 1px solid #E5E7EB;"><table cellpadding="0" cellspacing="0" border="0"><tbody><tr><td style="font-size: 12px; color: #6B7280; padding-right: 12px;">Share:</td><td style="padding-right: 8px;"><a href="https://www.linkedin.com/sharing/share-offsite/?url=https%3A%2F%2Frenewalweekly.com%2Fissues%2Ftime-machine&utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="display: inline-block; width: 28px; height: 28px; background: #0A66C2; border-radius: 50%; text-align: center; line-height: 28px; color: white; text-decoration: none; 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line-height: 28px; color: white; text-decoration: none; font-size: 12px; font-weight: bold;">f</a></td></tr></tbody></table></div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><div style="display: flex; align-items: center; margin-bottom: 4px;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0;">THE PIPELINE</p></div><h2 style="font-size: 22px; font-weight: 700; margin: 0 0 20px 0; line-height: 1.3; font-family: 'Trebuchet MS', Helvetica, sans-serif;">Where stem cell science stands this week</h2><div style="padding: 16px 0; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; border-bottom: 1px solid #E5E7EB;"><table cellpadding="0" cellspacing="0" border="0" style="margin-bottom: 8px;"><tbody><tr><td style="font-size: 14px; letter-spacing: 2px; color: #7C3AED; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; padding-right: 12px; vertical-align: middle;">●─●─●─●</td><td style="font-size: 11px; font-weight: 700; color: #7C3AED; text-transform: uppercase; letter-spacing: 0.5px; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; vertical-align: middle;">PUBLISHED</td></tr></tbody></table><p style="font-size: 15px; font-weight: 600; margin: 0 0 6px 0; line-height: 1.4; font-family: 'Trebuchet MS', Helvetica, sans-serif;">New Screening Method to Detect Cancer Cells in Cell Therapies</p><p style="font-size: 14px; color: #4B5563; margin: 0 0 8px 0; line-height: 1.5; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;">Finally, by systematizing the digital analysis system for the LACF assay (D-LACF assay), which streamlines the overall workflow from the performanc...</p><a href="https://pubmed.ncbi.nlm.nih.gov/41532030/?fc=20251204105706&ff=20260114105209&v=2.18.0.post22+67771e2&utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="font-size: 13px; color: #7C3AED; text-decoration: none; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;">Published Dec 19, 2025 →</a></div><div style="padding: 16px 0; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; border-bottom: 1px solid #E5E7EB;"><table cellpadding="0" cellspacing="0" border="0" style="margin-bottom: 8px;"><tbody><tr><td style="font-size: 14px; letter-spacing: 2px; color: #7C3AED; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; padding-right: 12px; vertical-align: middle;">●─●─●─●</td><td style="font-size: 11px; font-weight: 700; color: #7C3AED; text-transform: uppercase; letter-spacing: 0.5px; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; vertical-align: middle;">PUBLISHED</td></tr></tbody></table><p style="font-size: 15px; font-weight: 600; margin: 0 0 6px 0; line-height: 1.4; font-family: 'Trebuchet MS', Helvetica, sans-serif;">How a Protein Helps Pancreatic Cancer Spread: Molecular Study</p><p style="font-size: 14px; color: #4B5563; margin: 0 0 8px 0; line-height: 1.5; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;">Pancreatic adenocarcinoma (PAAD) is a highly aggressive malignant tumor of the gastrointestinal tract. Goosecoid (GSC), translated from a homeobox ...</p><a href="https://pubmed.ncbi.nlm.nih.gov/41532321/?fc=20251204105706&ff=20260114105209&v=2.18.0.post22+67771e2&utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="font-size: 13px; color: #7C3AED; text-decoration: none; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;">Published Jan 14, 2026 →</a></div><div style="padding: 16px 0; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; "><table cellpadding="0" cellspacing="0" border="0" style="margin-bottom: 8px;"><tbody><tr><td style="font-size: 14px; letter-spacing: 2px; color: #7C3AED; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; padding-right: 12px; vertical-align: middle;">●─●─●─●</td><td style="font-size: 11px; font-weight: 700; color: #7C3AED; text-transform: uppercase; letter-spacing: 0.5px; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; vertical-align: middle;">PUBLISHED</td></tr></tbody></table><p style="font-size: 15px; font-weight: 600; margin: 0 0 6px 0; line-height: 1.4; font-family: 'Trebuchet MS', Helvetica, sans-serif;">Stem Cell Therapy Shows Promising Nerve Repair Potential After Spinal Injury</p><p style="font-size: 14px; color: #4B5563; margin: 0 0 8px 0; line-height: 1.5; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;">Glial metabolic reprogramming is essential for axonal regeneration post-spinal cord injury (SCI). While olfactory mucosa mesenchymal stem cell-deri...</p><a href="https://pubmed.ncbi.nlm.nih.gov/41532272/?fc=20251204105706&ff=20260114105209&v=2.18.0.post22+67771e2&utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="font-size: 13px; color: #7C3AED; text-decoration: none; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;">Published Jan 14, 2026 →</a></div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">RESEARCH ROUNDUP</p><h2 style="font-size: 22px; font-weight: 700; margin: 0 0 4px 0; line-height: 1.3; font-family: 'Trebuchet MS', Helvetica, sans-serif;">Aging in Reverse</h2><div style="margin: 12px -24px;"><img src="https://imgur.com/JeHent3.jpg" alt="woman in the lab" style="width: 100%; display: block;"></div><p style="font-size: 11px; color: #6B7280; font-style: italic; margin: 4px 0 12px 0;">Jan 13, 2026 | pubmed</p><div style="font-size: 16px; line-height: 1.6;"><p style="margin: 0 0 8px 0;">Scientists working on cellular reprogramming have <a href="https://pubmed.ncbi.nlm.nih.gov/41528804/?fc=20251128131039&ff=20260114144726&v=2.18.0.post22+67771e2&utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">discovered</a> a way to reset aging cells using small molecules that act like "molecular time machines." The technique converts old, worn-out cells back into a youthful, pluripotent stem cell state by rewinding their epigenetic clock.</p><p style="margin: 0 0 8px 0;">The approach uses specific chemical compounds to reprogram cellular identity, essentially erasing the molecular signatures of aging and cellular damage. Instead of genetic manipulation, these small molecules can trigger the same reprogramming process that turns any cell type back into an embryonic-like state.</p><p style="margin: 0 0 8px 0;"><strong style="font-size: 18px; display: block; margin: 16px 0 8px 0;">Lab dish, not clinic</strong></p><p style="margin: 0 0 8px 0;">This research remains in early laboratory stages, with no human trials yet planned. The challenge lies in controlling the reprogramming process precisely enough to rejuvenate cells without triggering uncontrolled growth or other complications.</p><p style="margin: 0 0 8px 0;">If refined, the technique could eventually target age-related diseases by refreshing damaged tissues from within.</p></div><div style="margin-top: 16px; padding-top: 12px; border-top: 1px solid #E5E7EB;"><table cellpadding="0" cellspacing="0" border="0"><tbody><tr><td style="font-size: 12px; color: #6B7280; padding-right: 12px;">Share:</td><td style="padding-right: 8px;"><a href="https://www.linkedin.com/sharing/share-offsite/?url=https%3A%2F%2Frenewalweekly.com%2Fissues%2Ftime-machine&utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="display: inline-block; width: 28px; height: 28px; background: #0A66C2; border-radius: 50%; text-align: center; line-height: 28px; color: white; text-decoration: none; font-size: 12px; font-weight: bold;">in</a></td><td style="padding-right: 8px;"><a href="https://twitter.com/intent/tweet?text=Aging+in+Reverse&url=https%3A%2F%2Frenewalweekly.com%2Fissues%2Ftime-machine&utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="display: inline-block; width: 28px; height: 28px; background: #000000; border-radius: 50%; text-align: center; line-height: 28px; color: white; text-decoration: none; font-size: 12px; font-weight: bold;">X</a></td><td><a href="https://www.facebook.com/sharer/sharer.php?u=https%3A%2F%2Frenewalweekly.com%2Fissues%2Ftime-machine"e=Aging+in+Reverse&utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="display: inline-block; width: 28px; height: 28px; background: #1877F2; border-radius: 50%; text-align: center; line-height: 28px; color: white; text-decoration: none; font-size: 12px; font-weight: bold;">f</a></td></tr></tbody></table></div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px 24px 12px 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">PRESENTED BY Seed</p><h2 style="font-size: 22px; font-weight: 700; margin: 0 0 6px 0; font-family: 'Trebuchet MS', Helvetica, sans-serif;">Most probiotics don't survive digestion. This one does.</h2><div style="margin: 0 -24px 16px -24px;"><a href="https://seedhealthinc.pxf.io/c/3937227/3257437/19848?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener sponsored"><img src="https://i.imgur.com/2hAPH75.jpg" alt="" style="width: 100%; display: block;"></a></div><div style="font-size: 16px; line-height: 1.6;"><p style="margin: 0 0 12px 0;">Your gut is home to trillions of microorganisms that influence everything from digestion to skin health to immunity. The problem? Most probiotics never make it past your stomach acid.</p><p style="margin: 0 0 12px 0;"><a href="https://seedhealthinc.pxf.io/c/3937227/3257437/19848?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">Seed's DS-01 Daily Synbiotic</a> is different. Their patented capsule-in-capsule technology shields 24 clinically-studied probiotic strains until they reach your colon, where they actually work. It's a 2-in-1 prebiotic + probiotic formulated for digestive health, gut immunity, skin clarity, and even heart health.</p><p style="margin: 0 0 12px 0;">Unlike most supplements, every strain in DS-01 has been validated in human clinical trials. No refrigeration needed. No bloating. Just science that survives.</p><p style="margin: 0 0 12px 0;"><a href="https://seedhealthinc.pxf.io/c/3937227/3257437/19848?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">Take the 2-minute quiz</a> to unlock 20% off your first month.</p></div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">STEM CELLS</p><h2 style="font-size: 22px; font-weight: 700; margin: 0 0 6px 0; line-height: 1.3; font-family: 'Trebuchet MS', Helvetica, sans-serif;">Your Gut's Secret Repair Mode</h2><div style="margin: 12px -24px;"><a href="https://www.nature.com/articles/s42003-026-09533-x?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer"><img src="https://imgur.com/yKTovqI.jpg" alt="artistic depiction of the gut as coral reef" style="width: 100%; display: block;"></a></div><p style="font-size: 11px; color: #6B7280; font-style: italic; margin: 4px 0 12px 0; text-align: left;">Jan 12, 2026 | Nature</p><div style="font-size: 16px; line-height: 1.6;"><p style="margin: 0 0 16px 0;">Think of your intestines like a smartphone that automatically updates its software overnight. Except instead of fixing apps, your gut is constantly replacing worn-out cells with fresh ones.</p><p style="margin: 0 0 16px 0;">New research from Communications Biology <a href="https://www.nature.com/articles/s42003-026-09533-x?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">reveals</a> something fascinating: when your intestinal lining gets damaged from stress, poor diet, or illness, specialized cells can actually "revert" back to their stem cell state to help with repairs. It's like having a backup crew that springs into action when things go wrong.</p><p style="margin: 0 0 16px 0;">The easiest way to support this natural repair process? Give your gut regular <strong>12-hour</strong> breaks between dinner and breakfast. This fasting window lets your intestinal cells focus on maintenance instead of constantly processing food.</p><p style="margin: 0 0 16px 0;">Your gut literally rebuilds itself every few days - might as well give it the best working conditions possible.</p></div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">On our radar</p><h2 style="font-size: 22px; font-weight: 700; margin: 0 0 6px 0; font-family: 'Trebuchet MS', Helvetica, sans-serif;">Health breakthroughs worth watching</h2><div style="margin: 12px -24px;"><a href="https://pubmed.ncbi.nlm.nih.gov/41522156/?fc=20251128130949&ff=20260114154036&v=2.18.0.post22+67771e2&utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer"><img src="https://imgur.com/7ckgJRI.jpg" alt="woman in the lab studying" style="width: 100%; display: block;"></a></div><p style="font-size: 11px; color: #6B7280; font-style: italic; margin: 4px 0 12px 0;">Jan 12, 2026 | pubmed</p><div style="padding-bottom: 24px; margin-bottom: 24px; border-bottom: 1px solid #E5E7EB;"><p style="font-size: 16px; line-height: 1.6; margin: 0;"><strong>Dual delivery shows promise</strong> Combining inhaled and intravenous stem cell therapy proved more effective than single routes in treating acute respiratory distress syndrome. Researchers <a href="https://pubmed.ncbi.nlm.nih.gov/41522156/?fc=20251128130949&ff=20260114154036&v=2.18.0.post22+67771e2&utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">found</a> that inhalation rapidly reduces lung inflammation while IV delivery manages systemic effects. The dual approach could offer new options for ARDS patients facing limited treatment choices.</p></div><div style="padding-bottom: 24px; margin-bottom: 24px; border-bottom: 1px solid #E5E7EB;"><p style="font-size: 16px; line-height: 1.6; margin: 0;"><strong>Heart cells face transplant hurdles</strong> Lab-grown heart muscle cells show promise for treating heart failure, but significant challenges remain before clinical use. Scientists <a href="https://pubmed.ncbi.nlm.nih.gov/41522237/?fc=20251128130949&ff=20260114110445&v=2.18.0.post22+67771e2&utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">highlighted</a> advances in creating functional cardiomyocytes while noting integration and safety concerns. The field continues pursuing solutions for millions facing heart disease worldwide.</p></div><div style="padding-bottom: 24px; margin-bottom: 24px; "><p style="font-size: 16px; line-height: 1.6; margin: 0;"><strong>Gut cells revert under stress</strong> Intestinal cells can reverse their development to become stem cells when the gut faces damage, providing a backup repair system. Researchers <a href="https://www.nature.com/articles/s42003-026-09533-x?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">discovered</a> this cellular flexibility helps maintain gut health during stress or injury. The finding could inform treatments for inflammatory bowel diseases and other digestive disorders.</p></div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">CLINICAL TRIAL</p><h2 style="font-size: 22px; font-weight: 700; margin: 0 0 6px 0; line-height: 1.3; font-family: 'Trebuchet MS', Helvetica, sans-serif;">Eye implant restores sight</h2><div style="margin: 12px -24px;"><a href="https://www.sciencedaily.com/releases/2026/01/260108231348.htm?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer"><img src="https://www.sciencedaily.com/images/1920/retinal-implant-reverses-macular-degeneration.webp" alt="" style="width: 100%; display: block;"></a></div><p style="font-size: 11px; color: #6B7280; font-style: italic; margin: 4px 0 12px 0;">Jan 9, 2026 | ScienceDaily</p><div style="font-size: 16px; line-height: 1.6;"><p style="margin: 0 0 8px 0;">Scientists at USC are launching a new clinical trial for a hair-thin stem cell implant that could restore vision in people with advanced dry macular degeneration. The researchers <a href="https://www.sciencedaily.com/releases/2026/01/260108231348.htm?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">reported</a> that the tiny patch replaces damaged retinal cells responsible for sharp, central vision.</p><p style="margin: 0 0 8px 0;">The implant targets dry AMD, which affects <strong>11 million</strong> Americans and currently has no cure. Earlier safety studies showed the implant was well-tolerated and helped some patients see better. The new trial aims to prove the treatment can deliver meaningful, lasting improvements in eyesight. The patch contains stem cells that differentiate into retinal pigment epithelium, the layer of cells that supports photoreceptors in your eye.</p><p style="margin: 0 0 8px 0;"><strong style="font-size: 18px; display: block; margin: 16px 0 8px 0;">The early signs matter</strong></p><p style="margin: 0 0 8px 0;">What makes this significant isn't just the technology - it's the target. Dry AMD has been considered irreversible, with patients told to expect gradual vision loss. The implant represents a shift from managing the disease to potentially reversing damage.</p><p style="margin: 0 0 8px 0;">The trial is still recruiting patients, and results won't be available for months. Even if successful, the treatment would likely be expensive and limited to specialized centers initially.</p><p style="margin: 0 0 8px 0;">But for the millions watching their central vision fade, this represents something that hasn't existed before: the possibility that lost sight might actually come back. Previous approaches focused on slowing progression. This one aims to restore what's already gone.</p></div><div style="margin-top: 16px; padding-top: 12px; border-top: 1px solid #E5E7EB;"><table cellpadding="0" cellspacing="0" border="0"><tbody><tr><td style="font-size: 12px; color: #6B7280; padding-right: 12px;">Share:</td><td style="padding-right: 8px;"><a href="https://www.linkedin.com/sharing/share-offsite/?url=https%3A%2F%2Frenewalweekly.com%2Fissues%2Ftime-machine&utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="display: inline-block; width: 28px; height: 28px; background: #0A66C2; border-radius: 50%; text-align: center; line-height: 28px; color: white; text-decoration: none; font-size: 12px; font-weight: bold;">in</a></td><td style="padding-right: 8px;"><a href="https://twitter.com/intent/tweet?text=Eye+implant+restores+sight&url=https%3A%2F%2Frenewalweekly.com%2Fissues%2Ftime-machine&utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="display: inline-block; width: 28px; height: 28px; background: #000000; border-radius: 50%; text-align: center; line-height: 28px; color: white; text-decoration: none; font-size: 12px; font-weight: bold;">X</a></td><td><a href="https://www.facebook.com/sharer/sharer.php?u=https%3A%2F%2Frenewalweekly.com%2Fissues%2Ftime-machine"e=Eye+implant+restores+sight&utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="display: inline-block; width: 28px; height: 28px; background: #1877F2; border-radius: 50%; text-align: center; line-height: 28px; color: white; text-decoration: none; font-size: 12px; font-weight: bold;">f</a></td></tr></tbody></table></div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px 24px 12px 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">PRESENTED BY Viome</p><h2 style="font-size: 22px; font-weight: 700; margin: 0 0 6px 0; font-family: 'Trebuchet MS', Helvetica, sans-serif;">Your gut holds answers your doctor can't see.</h2><div style="margin: 0 -24px 16px -24px;"><a href="https://viomehq.sjv.io/c/3937227/1384802/13051?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener sponsored"><img src="https://i.imgur.com/Cvz4M4c.jpg" alt="" style="width: 100%; display: block;"></a></div><div style="font-size: 16px; line-height: 1.6;"><p style="margin: 0 0 12px 0;">Most health tests tell you what's wrong after symptoms appear. <a href="https://viomehq.sjv.io/c/3937227/1384802/13051?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">Viome's Full Body Intelligence Test</a> takes a different approach, analyzing your gut microbiome, cellular health, and biological age to reveal what's happening inside before problems start.</p><p style="margin: 0 0 12px 0;">Using advanced AI and RNA sequencing, Viome identifies the precise foods, supplements, and lifestyle changes your unique biology needs. No generic advice. Just personalized recommendations based on over 30 health insights.</p><p style="margin: 0 0 12px 0;">More than 500,000 people have already used Viome to optimize their health from the inside out. The test is simple: a quick at-home collection, lab analysis, and a personalized action plan delivered to your phone.</p><p style="margin: 0 0 12px 0;"><a href="https://viomehq.sjv.io/c/3937227/1384802/13051?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">Take the quiz</a> to see if Viome is right for you and get started on understanding your body at the cellular level.</p></div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">THE PULSE</p><h3 style="font-size: 18px; font-weight: 700; margin: 0 0 20px 0; font-family: 'Trebuchet MS', Helvetica, sans-serif;">Quick hits from the world of health innovation</h3><ul style="list-style: none; padding: 0; margin: 0;"><li style="font-size: 16px; line-height: 1.6; padding: 8px 0;">Scientists using small molecules successfully <a href="https://pubmed.ncbi.nlm.nih.gov/41528804/?fc=20251128131039&ff=20260114144726&v=2.18.0.post22+67771e2&utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">reversed</a> cellular aging in breakthrough senescence research.</li><li style="font-size: 16px; line-height: 1.6; padding: 8px 0;">Intestinal stem cells in stressed conditions can <a href="https://www.nature.com/articles/s42003-026-09533-x?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">revert</a> to fetal-like states for enhanced resilience.</li><li style="font-size: 16px; line-height: 1.6; padding: 8px 0;">Umbilical cord stem cell exosomes delivered via inhalation <a href="https://pubmed.ncbi.nlm.nih.gov/41522156/?fc=20251128130949&ff=20260114154036&v=2.18.0.post22+67771e2&utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">treated</a> acute respiratory distress syndrome effectively.</li><li style="font-size: 16px; line-height: 1.6; padding: 8px 0;">Heart muscle cells derived from pluripotent stem cells <a href="https://pubmed.ncbi.nlm.nih.gov/41522237/?fc=20251128130949&ff=20260114110445&v=2.18.0.post22+67771e2&utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">show</a> promise but face transplantation challenges.</li></ul></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; text-align: center; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 14px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 4px 0;">STAT OF THE WEEK</p><p style="font-size: 48px; font-weight: 800; color: #7C3AED; margin: 4px 0 12px 0; font-family: 'Trebuchet MS', Helvetica, sans-serif;">650 million</p><p style="font-size: 18px; font-style: italic; color: #4B5563; margin: 0 0 20px 0;"><em>people worldwide could benefit from stem cell heart therapy</em></p><div style="margin: 12px -24px;"><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC12779562/?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer"><img src="https://imgur.com/I56b5Hb.jpg" alt="huamn heart illustration" style="width: 100%; display: block;"></a></div><p style="font-size: 11px; color: #6B7280; font-style: italic; margin: 4px 0 12px 0; text-align: left;">Jan 12, 2026 | pubmed</p><div style="font-size: 16px; line-height: 1.6; text-align: left;"><p style="margin: 0 0 16px 0;">That's not a typo. Heart disease affects roughly 1 in 8 people globally, making it the world's leading killer. Traditional treatments can manage symptoms, but they can't repair dead heart muscle after a heart attack.</p><p style="margin: 0 0 16px 0;">Researchers <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC12779562/?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">reviewed</a> the latest progress in using lab-grown heart cells from stem cells to actually regenerate damaged heart tissue after heart attacks.</p><p style="margin: 0 0 16px 0;">If you've had a heart attack or know someone who has, this represents hope beyond current treatments that only prevent further damage. These therapies could potentially restore heart function instead of just managing decline.</p><p style="margin: 0 0 16px 0;">Scientists are getting closer to growing replacement heart muscle in the lab to repair hearts damaged by heart attacks.</p></div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">RECS</p><div style="margin: 12px -24px;"><img src="https://i.imgur.com/o5gsn9q.jpg" alt="" style="width: 100%; display: block;"></div><p style="margin: 8px 0; font-size: 16px; line-height: 1.6;"><strong>Read:</strong><a href="https://amzn.to/4pzllPv?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener sponsored" style="color: #1F2937; text-decoration: none; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;"> Breath</a> by James Nestor reveals the lost art of breathing</p><p style="margin: 8px 0; font-size: 16px; line-height: 1.6;"><strong>Watch:</strong> Dan Buettner on <a href="https://www.ted.com/talks/dan_buettner_how_to_live_to_be_100?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener sponsored" style="color: #1F2937; text-decoration: none; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">how to live to be 100+</a> (19 min)</p><p style="margin: 8px 0; font-size: 16px; line-height: 1.6;"><strong>Try:</strong><a href="https://transparentlabs.sjv.io/Bnm9L9?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener sponsored" style="color: #1F2937; text-decoration: none; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;"> Natural Testosterone</a> supplementation</p><p style="margin: 8px 0; font-size: 16px; line-height: 1.6;"><strong>Listen:</strong> Matt Walker's <a href="https://www.sleepdiplomat.com/podcast?utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" rel="noopener sponsored" style="color: #1F2937; text-decoration: none; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">Sleep Diplomat</a> appearances are always illuminating</p><p style="font-size: 12px; color: #6B7280; margin-top: 16px; padding-top: 12px; border-top: 1px solid #E5E7EB;"> *these are suggestions from our editorial team; these are not sponsorships or affiliate links </p></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; text-align: center; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">SHARE RENEWAL WEEKLY</p><div style="margin: 12px -24px;"><img src="https://i.imgur.com/kx7sCRJ.jpg" alt="" style="width: 100%; display: block;"></div><p style="font-size: 16px; line-height: 1.6; margin-bottom: 16px; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;">Share Renewal Weekly with someone who wants to stay ahead of the science. <strong>Refer 1 friend and get our free Healthy Diet Guide PDF</strong>, a science-backed roadmap to eating well.</p><p style="margin-bottom: 16px;">Your referral count: <strong>0</strong></p><a href="https://renewalweekly.com/subscribe?ref=PLACEHOLDER&utm_source=renewal-weekly.beehiiv.com&utm_medium=referral&utm_campaign=issue-6-time-machine" style="display: inline-block; padding: 12px 32px; background: #7C3AED; color: white; border-radius: 8px; text-decoration: none; font-weight: 600;">Share Now</a><p style="font-size: 12px; color: #6B7280; margin-top: 12px; margin-bottom: 0; word-break: break-all;">https://renewalweekly.com/subscribe?ref=PLACEHOLDER</p></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;">PLAY</p><div style="margin: 12px -24px;"><img src="https://i.imgur.com/n1K8qvq.jpg" alt="" style="width: 100%; display: block;"></div><p style="color: #4B5563; font-size: 16px; line-height: 1.6; margin-bottom: 16px; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;">Ready to test your health knowledge? This fun trivia challenge will stretch your mind and reveal some surprising insights about wellness and longevity.</p><div style="background: #F9FAFB; border-radius: 8px; padding: 12px 16px; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; line-height: 1.6; font-size: 16px;"> 1. Which of these activities has been shown to have the most significant impact on brain health as we age?<br>A) Crossword puzzles<br>B) Learning a new language<br>C) Playing video games<br>D) Meditation<br><br>2. How many minutes of moderate exercise per week are recommended for adults 45-75 to maintain optimal health?<br>A) 75 minutes<br>B) 150 minutes<br>C) 225 minutes<br>D) 300 minutes<br><br>3. Which nutrient is most crucial for maintaining muscle mass after age 50?<br>A) Vitamin D<br>B) Calcium<br>C) Protein<br>D) Magnesium </div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #F9FAFB; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><div style="text-align: center; margin-bottom: 20px; padding-bottom: 20px; border-bottom: 1px solid #E5E7EB;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 8px 0;">ONE QUICK QUESTION</p><p style="font-size: 18px; font-weight: 600; margin: 0 0 8px 0; font-family: 'Trebuchet MS', Helvetica, sans-serif;">What's one health habit you're trying to build this month?</p><p style="font-size: 14px; margin: 0 0 4px 0;">Hit reply and let us know. We read every response.</p><p style="font-size: 12px; color: #6B7280; font-style: italic; margin: 0;">(Replies also help our emails land in your inbox instead of spam. Win-win.)</p></div><table width="100%" cellpadding="0" cellspacing="0" border="0"><tbody><tr><td width="48%" style="vertical-align: top; padding-right: 12px;"><p style="font-weight: 600; margin: 0 0 8px 0; font-family: 'Trebuchet MS', Helvetica, sans-serif;">ANSWER</p><p style="font-size: 14px; color: #4B5563; margin: 0;">1. B) Learning a new language - Studies show complex cognitive activities like language learning create new neural connections and can delay cognitive decline by up to 4-5 years. 2. B) 150 minutes - The CDC recommends 150 minutes of moderate aerobic activity or 75 minutes of vigorous activity weekly for optimal health benefits. 3. C) Protein - Adults over 50 need more protein to combat age-related muscle loss, with experts recommending 1-1.2 grams per kilogram of body weight daily.</p></td><td width="4%" style="vertical-align: top;"></td><td width="48%" style="vertical-align: top; padding-left: 12px; border-left: 1px solid #E5E7EB;"><p style="font-weight: 600; margin: 0 0 8px 0; font-family: 'Trebuchet MS', Helvetica, sans-serif;">Word of the Day</p><p style="font-size: 14px; color: #4B5563; margin: 0;"><strong>Neuroplasticity</strong>: Your brain's ability to rewire and reorganize itself, creating new neural connections in response to learning, experience, or injury - like a mental GPS that can dynamically reroute when a path is blocked</p></td></tr></tbody></table></div></div></div></div></div></div></body></html>
