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!important;'><div class='rendered-post' style='max-width: 672px; margin: 0 auto;'><div class='bg-wt-background text-wt-text-on-background'><div style='padding-top:1.5rem; padding-bottom:1.5rem;'><style> .bh__byline_wrapper { font-size: .875rem; line-height: 1.25rem; vertical-align: middle; justify-content: space-between; display: block; } .bh__byline_social_wrapper { display: flex; margin-top: 0.5rem; align-items: center; } .bh__byline_social_wrapper > * + * { margin-left: 0.5rem; } @media (min-width: 768px) { .bh__byline_wrapper { display: flex; } .bh__byline_social_wrapper { margin-top: 0rem; } } </style><div id='web-header' style='padding-left: 2px; padding-right: 2px; color: var(--wt-text-on-background-color) !important; padding-bottom: 2rem;'><h1 style='font-size: 36px; font-family:'Trebuchet MS','Lucida Grande',Tahoma,sans-serif; line-height: 2.5rem; padding-bottom: 8px; font-weight: 700;'>Issue #1</h1><div class='bh__byline_wrapper'><div><div style='display:flex;'><div style='display:flex; flex-direction:row; justify-content:flex-start;'><div style='display:flex;'></div><div style='display:flex; align-items:center;'><p style='left:24px;position:relative;font-family:'Helvetica',Arial,sans-serif;font-weight:400;font-size:14px;color: var(--wt-text-on-background-color);margin:0px;line-height:20px;'><span class='text-wt-text-on-background' style='opacity:0.75;'> December 11, 2025 </span></p></div></div></div></div><div class='bh__byline_social_wrapper'><a href='https://www.facebook.com/sharer/sharer.php?u=https%3A%2F%2Fwww.renewalweekly.com%2Fp%2Fissue-1-cell-service-restored' target='_blank'><div style='max-width:28px;'><svg fill='none' height='100%' viewBox='0 0 212 212' width='100%' xmlns='http://www.w3.org/2000/svg'><circle cx='106.214' cy='105.5' fill-opacity='0.15' fill='#9CA3AF' r='105.5'></circle><path d='M96.9223 92.1778H87.0327V105.498H96.9223V145.461H113.405V105.498H125.273L126.591 92.1778H113.405V86.5165C113.405 83.5193 114.064 82.1873 117.031 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padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><table style="width: 100%; padding-bottom: 12px; margin-bottom: 16px; font-size: 13px; color: #6B7280; border-bottom: 1px solid #E5E7EB; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;" cellpadding="0" cellspacing="0"><tbody><tr><td style="text-align: left; width: 50%;">Issue #1</td><td style="text-align: right; width: 50%;">Dec 11, 2025</td></tr></tbody></table><div style="margin-bottom: 16px; border-radius: 8px; overflow: hidden;"><img src="https://i.imgur.com/dUcJfmW.jpg" alt="Renewal Weekly" style="width: 100%; display: block;"></div><table style="width: 100%; padding: 16px 0; margin-bottom: 16px;" cellpadding="0" cellspacing="0"><tbody><tr><td style="text-align: center; vertical-align: middle;"><span style="font-size: 11px; font-weight: 600; letter-spacing: 1px; color: #6B7280; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; margin-right: 12px;">PRESENTED BY</span><a href="https://viomehq.sjv.io/c/3937227/2137656/13051?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="vertical-align: middle;"><img src="https://i.imgur.com/ulqtEkV.png" alt="Partner" style="max-width: 120px; max-height: 32px; display: inline-block; vertical-align: middle;"></a></td></tr></tbody></table><div class="rw-body" style="font-size: 16px; line-height: 1.6; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"> December brings that familiar mix of holiday joy and winter fatigue—a reminder that our health truly is our greatest gift. Thank you for trusting us to keep you informed about the science that matters most to your well-being. </div><div style="margin-top: 16px;"><p style="font-size: 16px; font-weight: 600; margin-bottom: 12px; font-family: 'Trebuchet MS', Helvetica, sans-serif;">In today's edition:</p><ul style="list-style: none; padding: 0; margin: 0;"><li style="margin-bottom: 6px; font-size: 16px; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"> 🏥 HPV testing goes home </li><li style="margin-bottom: 6px; font-size: 16px; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"> 🔬 Off-the-shelf cancer breakthrough </li><li style="margin-bottom: 6px; font-size: 16px; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"> 🧬 Parkinson's stem cell success </li><li style="margin-bottom: 6px; font-size: 16px; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"> 📊 One donor, cancer risk </li></ul></div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">THIS WEEK'S BIG STORY</p><h2 style="font-size: 22px; font-weight: 700; margin: 0 0 6px 0; line-height: 1.3; font-family: 'Trebuchet MS', Helvetica, sans-serif;">HPV Self-Testing Gets Green Light</h2><div style="margin: 12px -24px;"><img src="https://imgur.com/gJJMVAo.jpg" alt="" style="width: 100%; display: block;"></div><p style="font-size: 11px; color: #6B7280; font-style: italic; margin: 4px 0 12px 0;">Dec 10, 2025 | Original image</p><div style="font-size: 16px; line-height: 1.6;"><p style="margin: 0 0 8px 0;">The American Cancer Society just endorsed self-collection for HPV testing in clinical settings, giving women ages 25 to 65 a new option for cervical cancer screening. The updated guidelines <a href="https://www.healthline.com/health-news/new-cervical-cancer-screening-guidelines-endorse-self-collection-hpv?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">recognize</a> that vaginal specimens collected by patients themselves are as accurate as those collected by clinicians.</p><p style="margin: 0 0 8px 0;">The change addresses a major barrier to cervical cancer screening: <strong>14 million</strong> women in the U.S. aren't up to date on their screenings, often due to discomfort, scheduling conflicts, or lack of access to healthcare providers. Self-collection uses a simple vaginal swab that patients can perform privately in a clinical setting, then hand to their provider for HPV testing.</p><p style="margin: 0 0 8px 0;"><strong style="font-size: 18px; display: block; margin: 16px 0 8px 0;">This isn't at home testing</strong> The collection still happens in a doctor's office, but patients do the swab themselves rather than having a full pelvic exam. The shift reflects growing evidence that HPV testing is more effective than Pap smears at detecting precancerous changes. HPV causes virtually all cervical cancers, and the virus can be detected years before cells become cancerous. </p><p style="margin: 0 0 8px 0;">Countries like Australia and the Netherlands have already implemented self-collection programs with success rates above <strong>90%</strong> for patient acceptance. For the roughly 4,000 women who die from cervical cancer annually in the U.S., removing barriers to screening could be lifesaving.</p></div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><div style="display: flex; align-items: center; margin-bottom: 4px;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0;">THE PIPELINE</p></div><h2 style="font-size: 22px; font-weight: 700; margin: 0 0 20px 0; line-height: 1.3; font-family: 'Trebuchet MS', Helvetica, sans-serif;">Where stem cell science stands this week</h2><div style="padding: 16px 0; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; border-bottom: 1px solid #E5E7EB;"><table cellpadding="0" cellspacing="0" border="0" style="margin-bottom: 8px;"><tbody><tr><td style="font-size: 14px; letter-spacing: 2px; color: #7C3AED; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; padding-right: 12px; vertical-align: middle;">●─●─●─●</td><td style="font-size: 11px; font-weight: 700; color: #7C3AED; text-transform: uppercase; letter-spacing: 0.5px; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; vertical-align: middle;">PUBLISHED</td></tr></tbody></table><p style="font-size: 15px; font-weight: 600; margin: 0 0 6px 0; line-height: 1.4; font-family: 'Trebuchet MS', Helvetica, sans-serif;">Mesenchymal Stem Cell-Derived Extracellular Vesicles in Alzheimer's Disease: A Novel Cell-Free Therapeutic Strategy and Diagnostic Biomarker </p><p style="font-size: 14px; color: #4B5563; margin: 0 0 8px 0; line-height: 1.5; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;">With the ongoing trend of population aging worldwide, the incidence of Alzheimer's disease (AD) is steadily increasing. In the absence of effective...</p><a href="https://pubmed.ncbi.nlm.nih.gov/41368288/?fc=20251204105706&ff=20251210125948&v=2.18.0.post22+67771e2&utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="font-size: 13px; color: #7C3AED; text-decoration: none; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;">Published Dec 10, 2025 →</a></div><div style="padding: 16px 0; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; border-bottom: 1px solid #E5E7EB;"><table cellpadding="0" cellspacing="0" border="0" style="margin-bottom: 8px;"><tbody><tr><td style="font-size: 14px; letter-spacing: 2px; color: #7C3AED; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; padding-right: 12px; vertical-align: middle;">●─●─●─●</td><td style="font-size: 11px; font-weight: 700; color: #7C3AED; text-transform: uppercase; letter-spacing: 0.5px; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; vertical-align: middle;">PUBLISHED</td></tr></tbody></table><p style="font-size: 15px; font-weight: 600; margin: 0 0 6px 0; line-height: 1.4; font-family: 'Trebuchet MS', Helvetica, sans-serif;">Cellular therapy in neuromyelitis optica spectrum disorder </p><p style="font-size: 14px; color: #4B5563; margin: 0 0 8px 0; line-height: 1.5; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;">Neuromyelitis optica spectrum disorder (NMOSD) is a debilitating neuroimmune condition characterized by recurrent inflammatory episodes that result...</p><a href="https://pubmed.ncbi.nlm.nih.gov/41368361/?fc=20251204105706&ff=20251210122616&v=2.18.0.post22+67771e2&utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="font-size: 13px; color: #7C3AED; text-decoration: none; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;">Published Dec 10, 2025 →</a></div><div style="padding: 16px 0; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; "><table cellpadding="0" cellspacing="0" border="0" style="margin-bottom: 8px;"><tbody><tr><td style="font-size: 14px; letter-spacing: 2px; color: #7C3AED; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; padding-right: 12px; vertical-align: middle;">●─●─●─●</td><td style="font-size: 11px; font-weight: 700; color: #7C3AED; text-transform: uppercase; letter-spacing: 0.5px; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; vertical-align: middle;">PUBLISHED</td></tr></tbody></table><p style="font-size: 15px; font-weight: 600; margin: 0 0 6px 0; line-height: 1.4; font-family: 'Trebuchet MS', Helvetica, sans-serif;">Multi-pathway therapeutics in colorectal cancer: Targeting EMT, CSCs, and non-apoptotic cell death for drug resistance reversal </p><p style="font-size: 14px; color: #4B5563; margin: 0 0 8px 0; line-height: 1.5; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;">Colorectal cancer (CRC) is a leading global malignancy, with therapeutic outcomes hampered by chemoresistance from epithelial-mesenchymal transitio...</p><a href="https://pubmed.ncbi.nlm.nih.gov/41367286/?fc=20251204105706&ff=20251210125948&v=2.18.0.post22+67771e2&utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="font-size: 13px; color: #7C3AED; text-decoration: none; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;">Published Dec 10, 2025 →</a></div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">CANCER RESEARCH</p><h2 style="font-size: 22px; font-weight: 700; margin: 0 0 4px 0; line-height: 1.3; font-family: 'Trebuchet MS', Helvetica, sans-serif;">Off-the-shelf breakthrough</h2><div style="margin: 12px -24px;"><img src="https://imgur.com/6676zSs.jpg" alt="" style="width: 100%; display: block;"></div><p style="font-size: 11px; color: #6B7280; font-style: italic; margin: 4px 0 12px 0;">Dec 10, 2025 | Original image</p><div style="font-size: 16px; line-height: 1.6;"><p style="margin: 0 0 8px 0;">Researchers studying aggressive multiple myeloma <a href="https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-researchers-find-new-hope-for-toughest-myeloma-through-off-the-shelf-immunotherapy/?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">found</a> that a dual-antibody therapy generated deep responses in extramedullary cases—the most treatment-resistant form of the blood cancer. This "off-the-shelf" immunotherapy combines two antibodies that target different proteins on cancer cells, requiring no genetic customization for individual patients. </p><p style="margin: 0 0 8px 0;"><strong style="font-size: 18px; display: block; margin: 16px 0 8px 0;">Key findings</strong></p><p style="margin: 0 0 8px 0;">The therapy produced what researchers called "powerful responses" in patients who had exhausted other options, though specific response rates weren't detailed in the announcement. The approach could offer hope for the roughly <strong>20%</strong> of myeloma patients who develop this aggressive form, where cancer cells escape the bone marrow and spread throughout the body.</p></div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px 24px 12px 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">PRESENTED BY Seed</p><h2 style="font-size: 22px; font-weight: 700; margin: 0 0 6px 0; font-family: 'Trebuchet MS', Helvetica, sans-serif;">Most probiotics don't survive digestion. This one does.</h2><div style="margin: 0 -24px 16px -24px;"><img src="https://i.imgur.com/2hAPH75.jpg" alt="" style="width: 100%; display: block;"></div><div style="font-size: 16px; line-height: 1.6;"><p style="margin: 0 0 12px 0;">Your gut is home to trillions of microorganisms that influence everything from digestion to skin health to immunity. The problem? Most probiotics never make it past your stomach acid.</p><p style="margin: 0 0 12px 0;"><a href="https://seedhealthinc.pxf.io/c/3937227/3257437/19848?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">Seed's DS-01 Daily Synbiotic</a> is different. Their patented capsule-in-capsule technology shields 24 clinically-studied probiotic strains until they reach your colon—where they actually work. It's a 2-in-1 prebiotic + probiotic formulated for digestive health, gut immunity, skin clarity, and even heart health.</p><p style="margin: 0 0 12px 0;">Unlike most supplements, every strain in DS-01 has been validated in human clinical trials. No refrigeration needed. No bloating. Just science that survives.</p><p style="margin: 0 0 12px 0;"><a href="https://seedhealthinc.pxf.io/c/3937227/3257437/19848?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">Take the 2-minute quiz</a> to unlock 20% off your first month.</p></div></div><div style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">STEM CELL RESEARCH</p><h2 style="font-size: 22px; font-weight: 700; margin: 0 0 4px 0; line-height: 1.3;">Parkinson's Cell Swap Success</h2><div style="margin: 12px -24px;"><img src="https://imgur.com/IGPolol.jpg" alt="" style="width: 100%; display: block;"></div><p style="font-size: 11px; color: #6B7280; font-style: italic; margin: 4px 0 12px 0;">Dec 11, 2025 | Unsplash</p><div style="font-size: 16px; line-height: 1.6;"><p style="margin: 0 0 8px 0;">Two groundbreaking clinical trials involving 19 Parkinson's patients demonstrated that scientists have successfully <a href="https://www.nature.com/articles/s41586-025-08845-y?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">transplanted</a> lab-grown dopamine neurons into human brains with zero serious adverse events after 18 months.</p><p style="margin: 0 0 8px 0;">One US-Canadian team used embryonic stem cells in 12 patients, while Japanese researchers tested induced pluripotent stem cells in 7 patients. Both trials showed the transplanted neurons survived and began producing dopamine—the crucial brain chemical lost in Parkinson's disease. Brain scans revealed an average <strong>44.7%</strong> increase in dopamine activity in the Japanese study, with even higher increases in patients receiving larger doses.</p><p style="margin: 0 0 8px 0;">The most encouraging finding: participants showed measurable motor improvements, with some experiencing visible reductions in tremors while maintaining their regular medications.</p><p style="margin: 0 0 8px 0;"><strong>Not so fast</strong></p><p style="margin: 0 0 8px 0;">These are early safety trials designed to test whether the approach works without causing harm—not to prove effectiveness. The real test comes in phase 3 trials starting later this year, which will need hundreds of patients and placebo controls to determine if stem cell therapy truly outperforms existing treatments like deep brain stimulation.</p><p style="margin: 0 0 8px 0;">Still, researchers are calling this a potential turning point for Parkinson's treatment, marking the first time scientists have successfully demonstrated that stem cell-derived neurons can survive and function in the human brain.</p></div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">On our radar</p><h2 style="font-size: 22px; font-weight: 700; margin: 0 0 6px 0; font-family: 'Trebuchet MS', Helvetica, sans-serif;">Health breakthroughs worth watching</h2><div style="margin: 12px -24px;"><img src="https://imgur.com/KDYcCXj.jpg" alt="" style="width: 100%; display: block;"></div><p style="font-size: 11px; color: #6B7280; font-style: italic; margin: 4px 0 12px 0;">Dec 10, 2025 | Original Image</p><div style="padding-bottom: 24px; margin-bottom: 24px; border-bottom: 1px solid #E5E7EB;"><p style="font-size: 16px; line-height: 1.6; margin: 0;"><strong>Longevity clinics set standards</strong> Industry leaders gathered to establish global standards for longevity medicine following explosive growth in anti-aging clinics worldwide. The Longevity Clinics Worldwide roundtable <a href="https://longevity.technology/news/the-future-of-longevity-clinics/?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">addressed</a> concerns about inconsistent practices and unproven treatments. The initiative aims to align science-based protocols across different countries and regulatory environments.</p></div><div style="padding-bottom: 24px; margin-bottom: 24px; border-bottom: 1px solid #E5E7EB;"><p style="font-size: 16px; line-height: 1.6; margin: 0;"><strong>FDA approves despite minimal data</strong> Gamida Cell's bone marrow therapy Omisirge gained FDA approval for severe aplastic anemia based on extremely limited clinical data. The agency <a href="https://ipscell.com/2025/12/gamida-cells-omisirge-for-saa-gets-ok-on-limited-data-more-low-data-fda-approvals-likely-to-come/?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">approved</a> the stem cell treatment despite concerns about the small patient population studied. This signals a trend toward more approvals with less comprehensive data for rare diseases.</p></div><div style="padding-bottom: 0px; margin-bottom: 8px; "><p style="font-size: 16px; line-height: 1.6; margin: 0;"><strong>Crohn's patient cycles continent</strong> A 62-year-old man with Crohn's disease cycled 4,500 miles from Alaska to Florida just years after major ostomy surgery at Mayo Clinic. After 41 years battling the condition, Moi Monroe <a href="https://newsnetwork.mayoclinic.org/discussion/mayo-patient-cycles-4500-miles-after-ostomy-surgery-for-crohns-disease/?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">completed</a> the cross-continental journey with his ostomy bag intact. His story demonstrates how surgical interventions can restore quality of life for patients with severe inflammatory bowel disease.</p></div></div><div style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">NUTRITION</p><h2 style="font-size: 22px; font-weight: 700; margin: 0 0 6px 0; line-height: 1.3;">Your morning oats may need an upgrade</h2><div style="margin: 12px -24px;"><img src="https://imgur.com/iYfDpk1.jpg" alt="" style="width: 100%; display: block;"></div><p style="font-size: 11px; color: #6B7280; font-style: italic; margin: 4px 0 12px 0;">Dec 11, 2025 | Originally generated image</p><div style="font-size: 16px; line-height: 1.6;"><p style="margin: 0 0 16px 0;">Think of your breakfast cereal as real estate—location matters, but so does the neighborhood. </p><p style="margin: 0 0 16px 0;">Nutrition researchers recently <a href="https://nutritionfacts.org/blog/mold-toxins-in-cereals-herbs-spices-and-wine/?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">discovered</a> that while most grains contain natural mold toxins, oats stand out as uniquely beneficial for gut health. The catch? Processing makes a huge difference. Steel-cut oats and whole oat groats feed your beneficial gut bacteria far better than rolled oats, which get crushed during processing and lose some of their prebiotic power.</p><p style="margin: 0 0 16px 0;"><strong>Here's your simple swap:</strong> Next grocery run, grab steel-cut oats instead of the rolled variety. Yes, they take <strong>15 minutes</strong> longer to cook, but you can make a big batch on Sunday and reheat portions all week.</p><p style="margin: 0 0 16px 0;">Your gut microbiome will thank you with better digestion and potentially stronger immunity.</p></div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px 24px 12px 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">PRESENTED BY Viome</p><h2 style="font-size: 22px; font-weight: 700; margin: 0 0 6px 0; font-family: 'Trebuchet MS', Helvetica, sans-serif;">Your gut holds answers your doctor can't see.</h2><div style="margin: 0 -24px 16px -24px;"><img src="https://i.imgur.com/Cvz4M4c.jpg" alt="" style="width: 100%; display: block;"></div><div style="font-size: 16px; line-height: 1.6;"><p style="margin: 0 0 12px 0;">Most health tests tell you what's wrong after symptoms appear. <a href="https://viomehq.sjv.io/c/3937227/1386011/13051?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">Viome's Full Body Intelligence Test</a> takes a different approach—analyzing your gut microbiome, cellular health, and biological age to reveal what's happening inside before problems start.</p><p style="margin: 0 0 12px 0;">Using advanced AI and RNA sequencing, Viome identifies the precise foods, supplements, and lifestyle changes your unique biology needs. No generic advice. Just personalized recommendations based on over 30 health insights.</p><p style="margin: 0 0 12px 0;">More than 500,000 people have already used Viome to optimize their health from the inside out. The test is simple: a quick at-home collection, lab analysis, and a personalized action plan delivered to your phone.</p><p style="margin: 0 0 12px 0;"><a href="https://viomehq.sjv.io/c/3937227/1386011/13051?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">Take the quiz</a> to see if Viome is right for you—and get started on understanding your body at the cellular level.</p></div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">WORTH KNOWING</p><h2 style="font-size: 22px; font-weight: 700; margin: 0 0 16px 0; line-height: 1.3; font-family: 'Trebuchet MS', Helvetica, sans-serif;">This week, keep these on your radar</h2><div style="background: #F9FAFB; border-radius: 8px; padding: 16px; margin-bottom: 12px;"><p style="font-weight: 600; margin: 0 0 10px 0;">Drive Sober This Season <span style="font-size: 12px; background: #EDE9FE; color: #7C3AED; padding: 2px 8px; border-radius: 4px; margin-left: 8px;">National Impaired Driving Prevention Month</span></p><p style="font-size: 16px; line-height: 1.6; margin: 0;">December is National Impaired Driving Prevention Month. With holiday parties and celebrations, now's the time to plan your safe rides home. Designate a driver, use rideshare apps, or arrange overnight stays. Even one drink can impair judgment—your life and others' lives depend on making the right choice.</p></div><div style="background: #F9FAFB; border-radius: 8px; padding: 16px; margin-bottom: 12px;"><p style="font-weight: 600; margin: 0 0 10px 0;">When Therapy Makes Sense </p><p style="font-size: 16px; line-height: 1.6; margin: 0;">Mental health counselors <a href="https://www.verywellmind.com/what-is-a-mental-health-counselor-4157925?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">can help</a> with more than just major crises: • Managing stress from work transitions or relationship changes • Developing coping skills for anxiety or depression symptoms • Processing grief, trauma, or major life adjustments • Building better communication and boundary-setting skills</p></div><div style="background: #F9FAFB; border-radius: 8px; padding: 16px; margin-bottom: 12px;"><p style="font-weight: 600; margin: 0 0 10px 0;">Motivation On Demand </p><p style="font-size: 16px; line-height: 1.6; margin: 0;">Need a mental boost during your commute or workout? <a href="https://www.verywellmind.com/best-motivational-podcasts-4769750?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">Motivational podcasts</a> offer science-backed strategies for everything from career goals to personal growth. Popular options include 'The Life Coach School Podcast' for mindset shifts and 'The Tim Ferriss Show' for high-achiever insights.</p></div><div style="background: #F9FAFB; border-radius: 8px; padding: 16px; margin-bottom: 12px;"><p style="font-weight: 600; margin: 0 0 10px 0;">Check Your Pantry Now </p><p style="font-size: 16px; line-height: 1.6; margin: 0;">Wegmans recalled deluxe mixed nuts <a href="https://www.everydayhealth.com/infectious-diseases/mixed-nuts-recalled-for-potential-salmonella-contamination/?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">due to salmonella risk</a> in pistachios. If you shop at stores along the Eastern Seaboard, check for any unsalted mixed nut products and discard them immediately. Salmonella can cause serious illness, especially in older adults and those with compromised immune systems.</p></div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; text-align: center; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 14px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 4px 0;">STAT OF THE WEEK</p><p style="font-size: 48px; font-weight: 800; color: #7C3AED; margin: 4px 0 12px 0; font-family: 'Trebuchet MS', Helvetica, sans-serif;">197 children</p><p style="font-size: 18px; font-style: italic; color: #4B5563; margin: 0 0 20px 0;"><em>fathered by one sperm donor carrying a cancer gene</em></p><div style="margin: 12px -24px;"><img src="https://media.cnn.com/api/v1/images/stellar/prod/gettyimages-1164513662-20251210112524503.jpg?c=16x9&q=w_800,c_fill" alt="" style="width: 100%; display: block;"></div><p style="font-size: 11px; color: #6B7280; font-style: italic; margin: 4px 0 12px 0; text-align: left;">Dec 10, 2025 | CNN Health</p><div style="font-size: 16px; line-height: 1.6; text-align: left;"><p style="margin: 0 0 16px 0;">That's not a typo. One European sperm donor with a rare genetic mutation that increases cancer risk fathered at least 197 children—some of whom have already died from the disease. To put this in perspective, that's roughly the size of an entire elementary school affected by one person's genetic legacy.</p><p style="margin: 0 0 16px 0;">Investigators <a href="https://www.cnn.com/2025/12/10/health/sperm-donor-cancer-investigation-scli-intl?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">discovered</a> this shocking number spans multiple countries across Europe, raising serious questions about genetic screening protocols in fertility clinics.</p><p style="margin: 0 0 16px 0;"><strong style="font-size: 18px; display: block; margin: 16px 0 8px 0;">Donor Screening is Essential</strong> This highlights the importance of asking clinics about their genetic screening processes. The ripple effects of inadequate testing can span generations. Fertility clinics need better genetic testing standards—and patients need to ask harder questions about donor screening before making life-changing decisions.</p></div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">THE PULSE</p><h3 style="font-size: 18px; font-weight: 700; margin: 0 0 20px 0; font-family: 'Trebuchet MS', Helvetica, sans-serif;">Quick hits from the world of health innovation</h3><ul style="list-style: none; padding: 0; margin: 0;"><li style="font-size: 16px; line-height: 1.6; padding: 8px 0;">Umbilical cord stem cells prevented dangerous blood clots in pregnancy complications when researchers <a href="https://pubmed.ncbi.nlm.nih.gov/41361768/?fc=20251128130949&ff=20251210161543&v=2.18.0.post22+67771e2&utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">tested</a> the therapy in laboratory studies.</li><li style="font-size: 16px; line-height: 1.6; padding: 8px 0;">Scientists restored lost regeneration abilities in simple organisms by manipulating cellular signaling pathways that <a href="https://www.nature.com/articles/s41467-025-66299-2?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">control</a> tissue repair.</li><li style="font-size: 16px; line-height: 1.6; padding: 8px 0;">Kidney disease rates varied significantly among ethnic groups in Toronto when researchers <a href="https://pubmed.ncbi.nlm.nih.gov/41365591/?fc=20251128131039&ff=20251210141007&v=2.18.0.post22+67771e2&utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">analyzed</a> dialysis patterns across populations.</li><li style="font-size: 16px; line-height: 1.6; padding: 8px 0;">Sterilization procedures extended lifespan across multiple animal species in analysis that <a href="https://www.nature.com/articles/s41586-025-09836-9?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">examined</a> reproductive status and longevity.</li><li style="font-size: 16px; line-height: 1.6; padding: 8px 0;">Genetic variations affect how diet impacts heart disease risk when specific gene types <a href="https://www.nature.com/articles/s41598-025-27399-7?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">interact</a> with different eating patterns.</li><li style="font-size: 16px; line-height: 1.6; padding: 8px 0;">Hospital meal composition significantly affects patient recovery outcomes when nutritionists <a href="https://www.nature.com/articles/s41430-025-01689-9?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">measured</a> protein and energy content.</li><li style="font-size: 16px; line-height: 1.6; padding: 8px 0;">Wearable sensors improved newborn survival rates in Ethiopian hospitals when medical teams <a href="https://medicalxpress.com/news/2025-12-wearable-advances-neonatal-health-ethiopia.html?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="text-decoration: none; color: #1F2937; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">deployed</a> continuous monitoring technology.</li></ul></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">RECS</p><div style="margin: 12px -24px;"><img src="https://i.imgur.com/o5gsn9q.jpg" alt="" style="width: 100%; display: block;"></div><p style="margin: 8px 0; font-size: 16px; line-height: 1.6;"><strong>Read:</strong><a href="https://www.amazon.com/Telomere-Effect-Revolutionary-Approach-Healthier/dp/1455587982?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="color: #1F2937; text-decoration: none; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">The Telomere Effect</a> by Nobel laureate Elizabeth Blackburn reveals how lifestyle affects aging</p><p style="margin: 8px 0; font-size: 16px; line-height: 1.6;"><strong>Watch:</strong> Optimizing Longevity with <a href="https://www.youtube.com/watch?v=JelnAdNFL2M&utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="color: #1F2937; text-decoration: none; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">Rhonda Patrick</a></p><p style="margin: 8px 0; font-size: 16px; line-height: 1.6;"><strong>Try:</strong><a href="https://www.breathwrk.com/?utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="color: #1F2937; text-decoration: none; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;"> Breathwrk</a> teaches breathing techniques</p><p style="margin: 8px 0; font-size: 16px; line-height: 1.6;"><strong>Listen:</strong><a href="https://open.spotify.com/episode/1fqRUG8Hk7Pp4V8uOTu3Yx?si=7f141c158ab5410e&utm_source=www.renewalweekly.com&utm_medium=referral&utm_campaign=issue-1" rel="noopener noreferrer" style="color: #1F2937; text-decoration: none; border-bottom: 2px solid #8B5CF6; padding-bottom: 1px; font-style: normal;">Longetivity Debate</a> covers truth about exercise, weight loss and creatine</p><p style="font-size: 12px; color: #6B7280; margin-top: 16px; padding-top: 12px; border-top: 1px solid #E5E7EB;"> *these are suggestions from our editorial team; these are not sponsorships or affiliate links </p></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;">PLAY</p><div style="margin: 12px -24px;"><img src="https://i.imgur.com/n1K8qvq.jpg" alt="" style="width: 100%; display: block;"></div><p style="color: #4B5563; font-size: 16px; line-height: 1.6; margin-bottom: 16px; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;">Ready to test your health smarts? This quiz will challenge what you know about wellness, longevity, and staying vibrant after 45.</p><div style="background: #F9FAFB; border-radius: 8px; padding: 12px 16px; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif; line-height: 1.6; font-size: 16px;"> 1. Which of these activities has been shown to have the MOST significant impact on brain health as we age?<br>A) Crossword puzzles<br>B) Regular exercise<br>C) Playing video games<br>D) Reading novels<br><br>2. How much daily exercise do most longevity experts recommend for adults 45-75?<br>A) 30 minutes of moderate activity<br>B) 10,000 steps<br>C) 2 hours of intense workout<br>D) No exercise needed<br><br>3. Which nutrient becomes MOST critical for maintaining muscle mass after age 50?<br>A) Vitamin D<br>B) Protein<br>C) Calcium<br>D) Iron </div></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #FFFFFF; overflow: visible; text-align: center; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 2px 0;">SHARE RENEWAL WEEKLY</p><div style="margin: 12px -24px;"><img src="https://i.imgur.com/HKjkNXM.jpg" alt="" style="width: 100%; display: block;"></div><p style="font-size: 16px; line-height: 1.6; margin-bottom: 16px; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;">Share Renewal Weekly with someone who wants to stay ahead of the science. Refer 3 friends and get our free Healthy Diet Guide PDF—a science-backed roadmap to eating well.</p><p style="margin-bottom: 16px;">Your referral count: <strong></strong></p><a href="https://www.renewalweekly.com/subscribe" style="display: inline-block; padding: 12px 32px; background: #7C3AED; color: white; border-radius: 8px; text-decoration: none; font-weight: 600;">Share Now</a></div><div class="rw-section" style="border: 1px solid #E5E7EB; border-radius: 12px; padding: 24px; margin-bottom: 16px; background: #F9FAFB; overflow: visible; font-family: Helvetica, -apple-system, BlinkMacSystemFont, sans-serif;"><div style="text-align: center; margin-bottom: 20px; padding-bottom: 20px; border-bottom: 1px solid #E5E7EB;"><p style="color: #7C3AED; font-size: 12px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.5px; margin: 0 0 8px 0;">ONE QUICK QUESTION</p><p style="font-size: 18px; font-weight: 600; margin: 0 0 8px 0; font-family: 'Trebuchet MS', Helvetica, sans-serif;">What's one health habit you're trying to build this month?</p><p style="font-size: 14px; margin: 0 0 4px 0;">Hit reply and let us know—we read every response.</p><p style="font-size: 12px; color: #6B7280; font-style: italic; margin: 0;">(Replies also help our emails land in your inbox instead of spam. Win-win.)</p></div><table width="100%" cellpadding="0" cellspacing="0" border="0"><tbody><tr><td width="48%" style="vertical-align: top; padding-right: 12px;"><p style="font-weight: 600; margin: 0 0 8px 0; font-family: 'Trebuchet MS', Helvetica, sans-serif;">ANSWER</p><p style="font-size: 14px; color: #4B5563; margin: 0;">1. B) Regular exercise - Physical activity stimulates neurogenesis and reduces cognitive decline by up to **40%**. 2. A) 30 minutes of moderate activity - This matches CDC guidelines and provides maximum health benefits with minimal risk. 3. B) Protein - Adults need more protein to combat age-related muscle loss, typically **1.2-1.5g per kg of body weight**.</p></td><td width="4%" style="vertical-align: top;"></td><td width="48%" style="vertical-align: top; padding-left: 12px; border-left: 1px solid #E5E7EB;"><p style="font-weight: 600; margin: 0 0 8px 0; font-family: 'Trebuchet MS', Helvetica, sans-serif;">Word of the Day</p><p style="font-size: 14px; color: #4B5563; margin: 0;"><strong>Cytology</strong>: The study of cells — how they're structured, function, and change — which helps doctors understand everything from normal growth to disease progression, like tracking HPV's impact on cervical health.</p></td></tr></tbody></table></div></div></div></div></div></div></body></html>
